Pentobarbital will lessen the extent or outcome of colchicine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. pentobarbital will reduce the level or effect of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. pentobarbital will minimize the extent or result of solifenacin by affecting hepatic/intestinal enzyme CYP3... https://nembutal-was-ist-das83681.answerblogs.com/31175751/what-does-is-nembutal-a-depressant-mean