In this article, we show that conolidine, a normal analgesic alkaloid used in classic Chinese drugs, targets ACKR3, thereby furnishing more proof of a correlation amongst ACKR3 and pain modulation and opening different therapeutic avenues for the remedy of Continual agony. In this case, it improves the Conolidine’s bioavailability, https://janetw581xtp0.wikievia.com/user