There exists a launch of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to minimize afferent agony transmission and produce analgesia. As a result, medications like clonidine that target alpha-2 receptors can affect the transmission of discomfort. Clonidine is a long-expression medication. https://neiln405dvm2.dailyblogzz.com/profile